汪海波个人简历

博士，二级教授，博士生导师

武汉轻工大学校长，国务院政府特殊津贴专家，国家食药局医疗器械审评专家组成员，湖北省自然科学创新群体负责人，湖北省优秀中青年科技创新团队负责人，武汉市农副资源循环利用与新产品开发工程技术中心主任

研究领域：天然生物质高值转化、水产胶原

电子邮件：wanghaibo@whpu.edu.cn

教育和工作经历：

n 1989年—1993年，武汉轻工大学，油脂工程，学士；

n 1997年—2000年，河南工业大学，食品科学，硕士；

n 2002年—2004年，华中农业大学，天然产物化学，博士；

n 1994年—至今，武汉轻工大学，专任教师

主要研究方向：

n 天然产物化学

n 天然生物材料

n 生物质化学化工

近年主持科研项目：

(1) 国家自然科学基金委员会, 面上项目, 胶原蛋白分子结构域多元化与人工重塑的实验学研究, 主持

(2) 国家自然科学基金委员会, 面上项目, 异源胶原的“杂化”纤维重组——现象、机制与新颖生物材料设计, 主持

(3) 国家自然科学基金委员会, 面上项目,鱼胶原体外自组装机制及其对胶原胶生物学性能的指针作用, 主持

(4) 国家自然科学基金委员会, 面上项目,淡水鱼胶原蛋白在生物医学材料领域中应用的相关基础问题研究, 主持

(5) 湖北省科技厅, 自然科学基金创新群体项目, 鱼加工副产物中天然胶原——面向新颖生物材料创制的应用基础研究, 主持

(6) 湖北省科技厅, 自然科学基金重点项目, 淡水鱼加工废弃物的生物吸附性能与机理, 主持

(7) 武汉市科学技术局, 应用基础前沿项目, 水产胶原跨域高值化利用的若干基础科学问题与系列新产品创制, 主持

(8) 武汉市科学技术局, 工程技术中心建设项目, 武汉市农副资源循环利用与新产品开发工程技术研究中心, 主持

(9) 武汉市科学技术局, 应用基础前沿项目, 鱼加工废弃物中胶原蛋白的体外纤维重组及新颖生物材料构建的关键技术研究, 主持

(10) 武汉市科学技术局, 应用基础前沿项目, 淡水鱼胶原蛋白在生物医学材料中的应用及其关键技术, 主持

近年代表性论文：

(1) Yuanjing Hou, Ruiming Guo, Fang Li, Desheng Fan, Chengzhi Xu, Lian Zhu, Juntao Zhang, Benmei Wei*, Haibo Wang*, Collagen-Fibronectin Crosstalk in Engineered Matrices: Synergistic Assembly Orchestrates Fibrillar Morphogenesis and Cell Adhesion-Migration Dynamics. Biomacromolecules, 2026, 27, 1819-1830.

(2) Lixia Liao*, Jiaqi Ding, Xiao Xiong, Fengjiao Quan, Xingxing Liu, Min Zhu, Zehui Chen, Sheng Li, Lian Zhu, Benmei Wei, Juntao Zhang, Haibo Wang*. Triple-Dynamic-Bond-Engineered Self-Healing Conductive Hydrogels for Deformation-Immune Flexible Supercapacitors and Wearable Epidermal Sensors. Biomacromolecules, 2026, 27, 805-821.

(3) Juntao Zhang*, Longxue Qiu, Haofei Xu, Yang Liu, Benmei Wei, Huizhi Kou, Chengzhi Xu, Lian Zhu, Haibo Wang*, Regulation of the hemostatic performance of collagen: on the role of hydrophilicity. Chemical Engineering Journal, 2025, 523, 168571.

(4) Lian Zhu*, Peng Mi, Zelong Yu, Qinghe Zhang, Lixia Liao, Benmei Wei, Haibo Wang*. Dual-modified selenium nanoparticles for the synergistic treatment of breast cancer. Materials Today Chemistry, 2025, 43, 102451.

(5) Huizhi Kou, Qingqiu Han, Chengzhi Xu, Lixia Liao, Yuanjing Hou, Haibo Wang*, Juntao Zhang*, The fibrillogenesis influence the binding specificity of collagen to discoidin domain receptor 2 and cell behavior. Colloids and Surfaces B: Biointerfaces, 2025, 250: 114554.

(6) Linjie Wang, Siying Huang, Delai Kang, Hui Wu, Lian Zhu, Yunjun Mei, Chengzhi Xu, Juntao Zhang*, Benmei Wei*, Haibo Wang*, Collagen-decorated drug-loaded polycaprolactone microspheres for breast cancer therapy in vitro and in vivo model. International Journal of Biological Macromolecules, 2025, 330, 147982.

(7) Haofei Xu, Yang Liu, Longxue Qiu, Antonio Lorenzo Masa Mbomio Mangue, Juntao Zhang*, Benmei Wei, Lian Zhu, Chengzhi Xu, Evgeny A. Shirshin, Haibo Wang*, Preparation and application of collagen-based hemostatic materials: a review. Collagen and Leather, 2025, 7, 11.

(8) Haofei Xu, Yang Liu, Yaozhi Huang, Juntao Zhang*, Zhenhua Qin, Benmei Wei, Chengzhi Xu, Lian Zhu, Haibo Wang*, The impact of spatial structures of collagen on the hemostatic properties of collagen/calcium alginate composite membranes. International Journal of Biological Macromolecules, 2025, 288, 138753.

(9) Wenyu Guo, Yuanyuan Zhang, Yunxuan Wang, Zhijun Hu, Peixuan Xu, Jingying Cai, Peirong Yu, Shiya Chen, Lei Zhang, Benmei Wei, Juntao Zhang, Sheng Li*, Haibo Wang*, Lingyun Chen, A water-soluble fluorescent probe derived from fish collagen peptides for multi-targeted detection of Cu²⁺ and Zn²⁺ ions via AIE and ESIPT mechanisms. Microchemical Journal, 2025, 215, 114313.

(10) Qinghe Zhang, Minghuan Dou, Xinyi Su, Zelong Yu, Benmei Wei, Lian Zhu*, Juntao Zhang*, Haibo Wang*, Collagen-based biomaterials: recent advances on regulating cell migration and correlated biomedical applications. Collagen and Leather, 2025, 7, 17.

(11) Chaonan Cai, Yuting Liu, Yuling Xu, Juntao Zhang, Benmei Wei, Chengzhi Xu*, Haibo Wang*. Mineral-element-chelating activity of food-derived collagen peptides: influencing factors and enhancement strategies. Critical Reviews in Food Science and Nutrition, 2025, 65, 3241-3255.

(12) Lixia Liao, Jiyuan Zhang, Jiaqi Ding, Chengzhi Xu, Lian Zhu, Yuanjing Hou, Sheng Li, Juntao Zhang, Benmei Wei, Haibo Wang*. Adhesive, Biocompatible, Antibacterial, and Degradable Collagen-Based Conductive Hydrogel as Strain Sensor for Human Motion Monitoring. Molecules, 2024, 29, 5728.

(13) Juntao Zhang, Yang Liu, Haofei Xu, Peishan Sui, Tianyi Liu, Mingming Zheng, Evgeny A. Shirshin, Benmei Wei, Chengzhi Xu, Haibo Wang*, The impact of N‑terminal modification of PAA with different chain lengths on the structure, thermal stability and pH sensitivity of succinylated collagen. Collagen and Leather, 2024, 6, 6.

(14) Juntao Zhang, Yang Liu, Haofei Xu, Peishan Sui, Benmei Wei, Chengzhi Xu, Lian Zhu, Mingming Zheng, Haibo Wang*. Fabrication and properties of hydrogel based on itaconic anhydride modified collagen. European Polymer Journal, 2024, 215, 113240.

(15) Yuanjing Hou, Fang Li, Wei Liu, Ruiming Guo, Hui Wu, Siying Huang, Chengzhi Xu, Lian Zhu, Juntao Zhang, Benmei Wei*, Haibo Wang*, Unraveling the role of integrating signal peptides into natural collagen on modulating cancer cell adhesion. International journal of biological macromolecules, 2024, 283, 137808.

(16) Lian Zhu, Yaxing Xiao, Hanling Zhu, Long Zuo, Chang Sun, Mingao Lei, Juntao Zhang, Benmei Wei, Chubo Qi*, Haibo Wang*. Fish-Derived Collagen: A Promising Biomaterial for Regulating the Migration Behavior of MCF-7 Cells. Advanced Engineering Materials, 2024, 26, 202400415.

(17) Lian Zhu*, Jialing Liu, Shuang Chen, Yuling Xu, Wei Wen*, Benmei Wei, Haibo Wang*. Modulating collagen configuration for flexibly regulating cell adhesion and migration behavior. European Polymer Journal, 2024, 217, 113292.

(18) Lian Zhu, Zelong Yu, Sheng Li, Chengzhi Xu, Yuanjing Hou, Lixia Liao, Yuling Xu, Juntao Zhang, Benmei Wei*, Wei Wen*, Haibo Wang*. Recent advances on collagen biomaterial: from extraction, cross-linking to tissue regeneration. Polymer Reviews, 2024, 64, 1031-1059.

(19) Benmei Wei, Siying Huang, Ke Li, Hui Wu, Yong Liu, Juntao Zhang, Yuanjing Hou, Lian Zhu, Chengzhi Xu*, Linjie Wang*, Haibo Wang*, Recognition of MCF-7 breast cancer cells using native collagen probes: Collagen source effect. International Journal of Biological Macromolecules, 2024, 282, 136661.

(20) Chengzhi Xu, Yuting Liu, Ke Li, Juntao Zhang, Benmei Wei*, Haibo Wang*, Absorption of food-derived peptides: Mechanisms, influencing factors, and enhancement strategies. Food Research International, 2024, 197, 115190.

(21) Chengzhi Xu, Chaonan Cai, Tianyi Liu, Jizhen Kang, Sheng Li, Juntao Zhang, Benmei Wei, Haibo Wang*. Enhancing the antioxidant activity of fish scale collagen peptides through plastein reaction. Food and Bioprocess Technology, 2024, 17, 3693-3703.

(22) Chengzhi Xu, Xiao Xiao, Wenjing Hu, Lian Zhu, Huizhi Kou, Juntao Zhang, Benmei Wei, Haibo Wang*. Ultrahigh Pressure Field: A friendly pathway for regulating the cellular adhesion and migration capacity of collagen. International Journal of Biological Macromolecules, 2024, 257, 127864.

教学课程：

n 胶原蛋白（本科生）

n 化学化工前沿（研究生）